There are several factors that help you determine your acceptable target database downtime, including:
How the target database is being used — If the target database is being used for reporting, then allowing the target database to be down for longer periods (upwards of one day) might not be an issue. However, if the target database serves as a disaster recovery database, the acceptable downtime is much less (possibly five to ten minutes or less).
Whether the target database is out of date — The determination of a database as out of date can be based on a specific time frame, or on the volume of data that needs to be applied to the database to synchronize the source and target databases. Once the out of date threshold is reached and you decide to disable replication, you will have to begin the replication enablement processes to restart the replication process.
